At 60 years of age, Look like 40 and feel like 20. Can You Do It?

What is Resveratrol?

70 years ago, the French paradox suggested that the French suffer a relatively low incidence of coronary heart disease and arthritis compared with other western nations, despite having a diet rich in saturated fats. It has been suggested that France's high red wine consumption is a primary factor in the trend. It is believed that one of the substances in red wine potentially related to this effect. This substance is called Resveratrol.

Resveratrol is a natural substance found in red wine that may help slowing down the ageing process. In the scientist experiments, cancer, anti-inflammatory, blood-sugar-regulation, arthritis and other beneficial cardiovascular effects of resveratrol have been reported. Research also indicates that antioxidants may help cancel out the cell-damaging.

What is Resveratrol? - Barbara Walters ABC

Resveratrol works on a gene called SIRT1 which is the gene controls the ageing process. Resveratrol seeks out that gene and switches it on. Dr David Sinclair

*Resveratrol is 100% herbal based supplements. It is not a prescription medicine. (disclaimer)

The Anti-aging Breakthrough

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Resveratrol may help Increase Healthy Lifespan

Scientists first noticed that feeding Resveratrol to yeast lengthened their lives by 70%. As they moved up the food chain in their experiments, they find a recurring theme: Resveratrol may help extend lifespan. A long awaited study headed by David Sinclair and released by Harvard Medical School published the results on mice. The average lifespan of the mice were increased by 30%. And this is despite the fact that resveratrol consumption began in mid-life. Overfed mice were studied in particular, and equally surpising was the fact that Resveratrol virtually eliminated the majority of other illnesses unique to the obese mouse control group.

Caloric Restriction and SIRT1 Activation

Caloric Restriction (CR) - severe limitation of food intake - has long been known to dramatically increase the lifespan of every animal we've tried it on. Scientific research shows it can push lifespan out by up to 55% in mice. Even mice beginning CR late in life have their lives extended by up to 35%. Sinclair has shown that a gene called Sirt1 is turned on by a CR diet, and that it is also turned on by Resveratrol. No other molecule is known to have this ability. Sinclair has demonstrated in rats that when the Sirt1 gene is activated, lifespan is increased, but CR does not increase it any further. Conversely, knocking out the Sirt1 gene eliminated any beneficial effect of CR. The evidence is very convincing at this point that Resveratrol may be CR in a pill.

A great overview of Resveratrol and its life extension benefits can be found in this 60 minutes

In a widely publicised report, researchers at Harvard Medical School and BIOMOL Laboratories have demonstrated that resveratrol activates a “longevity gene” by activating a cell’s survival defense enzyme, which prolongs the time cells have to repair their broken DNA.

One of the known causes of ageing and death is that older cells lose their ability to perfectly replicate DNA in every new cell. DNA “mistakes” accumulate and allow little pieces of DNA to become active and print themselves out, so to speak, creating a type of “DNA debris” that eventually stops a cell from functioning effectively. Resveratrol has been shown to reduce the frequency of “DNA debris” by 60% through the longevity gene that is stimulated.

Age-Related Health Benefits of Resveratrol

Animal on CR do not just live longer, but are healthier for longer. We are all but immune to a wide variety of diseases that most young animals (and people) are less prone to be troubled by. And this seems to be exactly the result of studies that have been made with Resveratrol. For example, in the now-famous Sinclair study, the livers were autopsied and they found that the high-calorie fed ones on Resveratrol had livers compatible with those on a far healtheir diet.

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